DENALI THERAPEUTICS INC

Ticker: DNLI CUSIP: 24823R105 Class: Common Stock

Vanguard Personalized Indexing Management, LLC's Holding History (CIK: 0001767306)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 11,736 Value ($000) $194 Avg Close $16.88 Range $13.75 - $20.61

Q3 2025

Shares 12,526 Value ($000) $182 Avg Close $14.37 Range $12.58 - $16.20

Q2 2025

Shares 15,329 Value ($000) $214 Avg Close $14.07 Range $10.57 - $16.97

Q4 2024

Shares 11,377 Value ($000) $232 Avg Close $25.60 Range $19.93 - $33.33

Q3 2024

Shares 12,890 Value ($000) $375 Avg Close $24.79 Range $19.74 - $32.13

Q2 2024

Shares 10,790 Value ($000) $249 Avg Close $19.20 Range $14.56 - $23.87

Q2 2021

Shares 6,012 Value ($000) $472 Avg Close $61.86 Range $49.20 - $79.70

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	11,736	$194	$16.88	$13.75 - $20.61
Q3 2025	12,526	$182	$14.37	$12.58 - $16.20
Q2 2025	15,329	$214	$14.07	$10.57 - $16.97
Q4 2024	11,377	$232	$25.60	$19.93 - $33.33
Q3 2024	12,890	$375	$24.79	$19.74 - $32.13
Q2 2024	10,790	$249	$19.20	$14.56 - $23.87
Q2 2021	6,012	$472	$61.86	$49.20 - $79.70