DENALI THERAPEUTICS INC

Ticker: DNLI CUSIP: 24823R105 Class: Common Stock

XTX Topco Ltd's Holding History (CIK: 0001828301)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 65,345 Value ($000) $949 Avg Close $14.37 Range $12.58 - $16.20

Q1 2025

Shares 13,485 Value ($000) $183 Avg Close $19.16 Range $13.30 - $24.34

Q4 2024

Shares 16,087 Value ($000) $328 Avg Close $25.60 Range $19.93 - $33.33

Q3 2023

Shares 44,656 Value ($000) $921 Avg Close $25.37 Range $20.52 - $30.79

Q4 2022

Shares 12,231 Value ($000) $340 Avg Close $29.75 Range $25.96 - $34.78

Q3 2022

Shares 12,023 Value ($000) $369 Avg Close $32.51 Range $25.88 - $39.43

Q1 2021

Shares 3,683 Value ($000) $210 Avg Close $66.94 Range $52.23 - $84.25

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	65,345	$949	$14.37	$12.58 - $16.20
Q1 2025	13,485	$183	$19.16	$13.30 - $24.34
Q4 2024	16,087	$328	$25.60	$19.93 - $33.33
Q3 2023	44,656	$921	$25.37	$20.52 - $30.79
Q4 2022	12,231	$340	$29.75	$25.96 - $34.78
Q3 2022	12,023	$369	$32.51	$25.88 - $39.43
Q1 2021	3,683	$210	$66.94	$52.23 - $84.25