DENALI THERAPEUTICS INC

Ticker: DNLI CUSIP: 24823R105 Class: Common Stock

Pathstone Holdings, LLC's Holding History (CIK: 0002011612)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 51,424 Value ($000) $849 Avg Close $16.88 Range $13.75 - $20.61

Q3 2025

Shares 45,830 Value ($000) $665 Avg Close $14.37 Range $12.58 - $16.20

Q2 2025

Shares 45,040 Value ($000) $630 Avg Close $14.07 Range $10.57 - $16.97

Q1 2025

Shares 38,305 Value ($000) $521 Avg Close $19.16 Range $13.30 - $24.34

Q4 2024

Shares 21,224 Value ($000) $433 Avg Close $25.60 Range $19.93 - $33.33

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	51,424	$849	$16.88	$13.75 - $20.61
Q3 2025	45,830	$665	$14.37	$12.58 - $16.20
Q2 2025	45,040	$630	$14.07	$10.57 - $16.97
Q1 2025	38,305	$521	$19.16	$13.30 - $24.34
Q4 2024	21,224	$433	$25.60	$19.93 - $33.33