DESIGN THERAPEUTICS INC

Ticker: DSGN CUSIP: 25056L103 Class: Common Stock

Nuveen, LLC's Holding History (CIK: 0001871926)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 125,260 Value ($000) $1,175 Avg Close $7.83 Range $5.28 - $10.31

Q3 2025

Shares 133,028 Value ($000) $1,002 Avg Close $5.01 Range $3.33 - $7.59

Q2 2025

Shares 133,028 Value ($000) $448 Avg Close $3.74 Range $2.60 - $5.04

Q1 2025

Shares 147,228 Value ($000) $568 Avg Close $4.77 Range $3.58 - $6.81

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	125,260	$1,175	$7.83	$5.28 - $10.31
Q3 2025	133,028	$1,002	$5.01	$3.33 - $7.59
Q2 2025	133,028	$448	$3.74	$2.60 - $5.04
Q1 2025	147,228	$568	$4.77	$3.58 - $6.81