DISC MEDICINE INC

Ticker: IRON CUSIP: 254604101 Class: Common Stock

BAKER BROS. ADVISORS LP's Holding History (CIK: 0001263508)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 337,050 Value ($000) $26,765 Avg Close $84.50 Range $65.26 - $99.50

Q3 2025

Shares 337,050 Value ($000) $22,272 Avg Close $59.49 Range $51.01 - $68.43

Q2 2025

Shares 337,050 Value ($000) $17,850 Avg Close $46.97 Range $30.82 - $55.52

Q1 2025

Shares 77,050 Value ($000) $3,825 Avg Close $55.60 Range $48.05 - $65.02

Q4 2024

Shares 77,050 Value ($000) $4,885 Avg Close $57.84 Range $44.81 - $68.73

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	337,050	$26,765	$84.50	$65.26 - $99.50
Q3 2025	337,050	$22,272	$59.49	$51.01 - $68.43
Q2 2025	337,050	$17,850	$46.97	$30.82 - $55.52
Q1 2025	77,050	$3,825	$55.60	$48.05 - $65.02
Q4 2024	77,050	$4,885	$57.84	$44.81 - $68.73