DYNE THERAPEUTICS INC

Ticker: DYN CUSIP: 26818M108 Class: Common Stock

BAKER BROS. ADVISORS LP's Holding History (CIK: 0001263508)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 813,449 Value ($000) $15,911 Avg Close $18.94 Range $12.33 - $25.00

Q1 2025

Shares 672,096 Value ($000) $7,030 Avg Close $14.30 Range $9.96 - $26.22

Q4 2024

Shares 672,096 Value ($000) $15,835 Avg Close $29.58 Range $23.05 - $35.90

Q3 2024

Shares 672,096 Value ($000) $24,142 Avg Close $39.80 Range $23.55 - $47.45

Q2 2024

Shares 672,096 Value ($000) $23,718 Avg Close $29.06 Range $23.11 - $36.60

Q1 2024

Shares 285,000 Value ($000) $8,091 Avg Close $22.62 Range $12.33 - $30.27

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	813,449	$15,911	$18.94	$12.33 - $25.00
Q1 2025	672,096	$7,030	$14.30	$9.96 - $26.22
Q4 2024	672,096	$15,835	$29.58	$23.05 - $35.90
Q3 2024	672,096	$24,142	$39.80	$23.55 - $47.45
Q2 2024	672,096	$23,718	$29.06	$23.11 - $36.60
Q1 2024	285,000	$8,091	$22.62	$12.33 - $30.27