DYNE THERAPEUTICS INC

Ticker: DYN CUSIP: 26818M108 Class: Common Stock

Polar Capital Holdings Plc's Holding History (CIK: 0001837309)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,269,131 Value ($000) $24,824 Avg Close $18.94 Range $12.33 - $25.00

Q3 2025

Shares 529,388 Value ($000) $6,697 Avg Close $11.41 Range $8.06 - $14.35

Q2 2023

Shares 500,000 Value ($000) $5,625 Avg Close $11.80 Range $8.04 - $15.02

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,269,131	$24,824	$18.94	$12.33 - $25.00
Q3 2025	529,388	$6,697	$11.41	$8.06 - $14.35
Q2 2023	500,000	$5,625	$11.80	$8.04 - $15.02