EDGEWISE THERAPEUTICS INC

Ticker: EWTX CUSIP: 28036F105 Class: Common Stock

D. E. Shaw & Co., Inc.'s Holding History (CIK: 0001009207)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 394,695 Value ($000) $9,794 Avg Close $20.07 Range $14.25 - $27.39

Q3 2025

Shares 677,561 Value ($000) $10,990 Avg Close $14.18 Range $12.30 - $17.00

Q2 2025

Shares 595,432 Value ($000) $7,806 Avg Close $14.42 Range $10.60 - $22.47

Q1 2025

Shares 140,548 Value ($000) $3,092 Avg Close $26.23 Range $21.52 - $30.48

Q4 2024

Shares 686,371 Value ($000) $18,326 Avg Close $31.84 Range $25.97 - $38.12

Q3 2024

Shares 455,348 Value ($000) $12,153 Avg Close $19.89 Range $15.02 - $30.00

Q2 2024

Shares 311,476 Value ($000) $5,610 Avg Close $17.44 Range $14.90 - $21.60

Q1 2024

Shares 473,680 Value ($000) $8,640 Avg Close $15.89 Range $9.00 - $20.69

Q4 2023

Shares 31,950 Value ($000) $350 Avg Close $7.02 Range $5.12 - $12.46

Q1 2023

Shares 24,736 Value ($000) $165 Avg Close $9.27 Range $6.39 - $11.48

Q4 2022

Shares 11,274 Value ($000) $101 Avg Close $9.37 Range $7.04 - $11.16

Q3 2021

Shares 13,695 Value ($000) $227 Avg Close $18.08 Range $13.60 - $24.30

Q2 2021

Shares 46,167 Value ($000) $985 Avg Close $27.34 Range $21.07 - $34.99

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	394,695	$9,794	$20.07	$14.25 - $27.39
Q3 2025	677,561	$10,990	$14.18	$12.30 - $17.00
Q2 2025	595,432	$7,806	$14.42	$10.60 - $22.47
Q1 2025	140,548	$3,092	$26.23	$21.52 - $30.48
Q4 2024	686,371	$18,326	$31.84	$25.97 - $38.12
Q3 2024	455,348	$12,153	$19.89	$15.02 - $30.00
Q2 2024	311,476	$5,610	$17.44	$14.90 - $21.60
Q1 2024	473,680	$8,640	$15.89	$9.00 - $20.69
Q4 2023	31,950	$350	$7.02	$5.12 - $12.46
Q1 2023	24,736	$165	$9.27	$6.39 - $11.48
Q4 2022	11,274	$101	$9.37	$7.04 - $11.16
Q3 2021	13,695	$227	$18.08	$13.60 - $24.30
Q2 2021	46,167	$985	$27.34	$21.07 - $34.99