ELEVEN BIOTHERAPEUTICS INC

CUSIP: 286221106 Class: CMN

RENAISSANCE TECHNOLOGIES LLC's Holding History (CIK: 0001037389)

Note: Option positions (PUT/CALL) are excluded.

Q2 2016
Shares 118,500 Value ($000) $198 Avg Close — Range —
Q1 2016
Shares 112,500 Value ($000) $36 Avg Close — Range —