ELEVEN BIOTHERAPEUTICS INC

CUSIP: 286221106 Class: CMN

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q1 2015
Shares 87,110 Value ($000) $777 Avg Close — Range —
Q4 2014
Shares 87,110 Value ($000) $1,035 Avg Close — Range —