ELIEM THERAPEUTICS INC

Ticker: CLYM CUSIP: 28658R106 Class: Common Stock

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 566,712 Value ($000) $2,267 Avg Close $2.40 Range $1.54 - $5.05

Q3 2025

Shares 112,681 Value ($000) $226 Avg Close $1.86 Range $1.19 - $2.55

Q2 2025

Shares 179,591 Value ($000) $223 Avg Close $1.24 Range $1.05 - $1.47

Q1 2025

Shares 255,114 Value ($000) $311 Avg Close $1.62 Range $1.20 - $2.36

Q4 2024

Shares 237,710 Value ($000) $428 Avg Close $3.62 Range $1.73 - $5.86

Q3 2024

Shares 23,514 Value ($000) $120 Avg Close $7.07 Range $4.75 - $9.21

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	566,712	$2,267	$2.40	$1.54 - $5.05
Q3 2025	112,681	$226	$1.86	$1.19 - $2.55
Q2 2025	179,591	$223	$1.24	$1.05 - $1.47
Q1 2025	255,114	$311	$1.62	$1.20 - $2.36
Q4 2024	237,710	$428	$3.62	$1.73 - $5.86
Q3 2024	23,514	$120	$7.07	$4.75 - $9.21