EPIZYME INC

CUSIP: 29428V104 Class: COM

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q4 2019
Shares 1,384,200 Value ($000) $34,051 Avg Close — Range —
Q3 2019
Shares 1,365,000 Value ($000) $14,080 Avg Close — Range —
Q2 2019
Shares 1,365,000 Value ($000) $17,131 Avg Close — Range —
Q1 2019
Shares 1,365,000 Value ($000) $16,912 Avg Close — Range —
Q4 2018
Shares 1,125,000 Value ($000) $6,930 Avg Close — Range —
Q3 2018
Shares 200,000 Value ($000) $2,120 Avg Close — Range —
Q2 2018
Shares 275,000 Value ($000) $3,726 Avg Close — Range —
Q1 2018
Shares 70,000 Value ($000) $1,242 Avg Close — Range —
Q1 2014
Shares 115,500 Value ($000) $2,630 Avg Close — Range —