EVOKE PHARMA INC

CUSIP: 30049G104 Class: COM

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q2 2016
Shares 130,000 Value ($000) $891 Avg Close — Range —
Q1 2016
Shares 130,000 Value ($000) $662 Avg Close — Range —
Q4 2015
Shares 130,000 Value ($000) $429 Avg Close — Range —
Q3 2015
Shares 260,000 Value ($000) $757 Avg Close — Range —
Q2 2015
Shares 259,100 Value ($000) $1,355 Avg Close — Range —
Q1 2015
Shares 245,000 Value ($000) $1,727 Avg Close — Range —
Q4 2014
Shares 240,000 Value ($000) $1,416 Avg Close — Range —
Q3 2014
Shares 267,000 Value ($000) $1,468,367 Avg Close — Range —
Q2 2014
Shares 242,500 Value ($000) $1,962 Avg Close — Range —
Q1 2014
Shares 233,400 Value ($000) $1,956 Avg Close — Range —