FIVE PRIME THERAPEUTICS INC

CUSIP: 33830X104 Class: COM

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q3 2017
Shares 40,000 Value ($000) $1,636 Avg Close — Range —
Q1 2017
Shares 40,000 Value ($000) $1,446 Avg Close — Range —
Q4 2016
Shares 40,000 Value ($000) $2,004 Avg Close — Range —
Q3 2016
Shares 60,000 Value ($000) $3,149 Avg Close — Range —
Q2 2016
Shares 60,000 Value ($000) $2,481 Avg Close — Range —
Q1 2016
Shares 80,000 Value ($000) $3,250 Avg Close — Range —
Q4 2015
Shares 145,000 Value ($000) $6,018 Avg Close — Range —
Q3 2015
Shares 175,000 Value ($000) $2,693 Avg Close — Range —
Q2 2015
Shares 125,000 Value ($000) $3,105 Avg Close — Range —
Q1 2014
Shares 90,000 Value ($000) $1,769 Avg Close — Range —