FLAMEL TECHNOLOGIES SA

CUSIP: 338488109 Class: SPON

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q4 2015
Shares 250,000 Value ($000) $3,053 Avg Close — Range —
Q3 2015
Shares 310,000 Value ($000) $5,056 Avg Close — Range —
Q2 2015
Shares 310,000 Value ($000) $6,569 Avg Close — Range —
Q1 2015
Shares 300,000 Value ($000) $5,394 Avg Close — Range —
Q4 2014
Shares 205,000 Value ($000) $3,512 Avg Close — Range —