FULCRUM THERAPEUTICS INC

Ticker: FULC CUSIP: 359616109 Class: 0

Darwin Global Management, Ltd.'s Holding History (CIK: 0001839209)

Note: Option positions (PUT/CALL) are excluded.

Q4 2021

Shares 317,428 Value ($000) $5,615 Avg Close $19.81 Range $12.19 - $28.88

Q3 2021

Shares 33,997 Value ($000) $959 Avg Close $18.95 Range $6.85 - $33.10

Q1 2021

Shares 49,868 Value ($000) $587 Avg Close $12.36 Range $10.54 - $15.75

Q4 2020

Shares 61,313 Value ($000) $718 Avg Close $11.31 Range $7.63 - $14.42

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2021	317,428	$5,615	$19.81	$12.19 - $28.88
Q3 2021	33,997	$959	$18.95	$6.85 - $33.10
Q1 2021	49,868	$587	$12.36	$10.54 - $15.75
Q4 2020	61,313	$718	$11.31	$7.63 - $14.42