GRAIL INC

Ticker: GRAL CUSIP: 384747101 Class: Common Stock

BAKER BROS. ADVISORS LP's Holding History (CIK: 0001263508)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 2,085,333 Value ($000) $178,484 Avg Close $86.40 Range $58.50 - $115.76

Q3 2025

Shares 1,630,125 Value ($000) $96,389 Avg Close $38.21 Range $29.95 - $59.70

Q2 2025

Shares 1,630,125 Value ($000) $83,821 Avg Close $36.20 Range $20.44 - $52.56

Q1 2025

Shares 1,630,125 Value ($000) $41,633 Avg Close $30.90 Range $16.56 - $63.99

Q4 2024

Shares 1,630,125 Value ($000) $29,098 Avg Close $16.26 Range $12.33 - $24.92

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	2,085,333	$178,484	$86.40	$58.50 - $115.76
Q3 2025	1,630,125	$96,389	$38.21	$29.95 - $59.70
Q2 2025	1,630,125	$83,821	$36.20	$20.44 - $52.56
Q1 2025	1,630,125	$41,633	$30.90	$16.56 - $63.99
Q4 2024	1,630,125	$29,098	$16.26	$12.33 - $24.92