GRAIL INC

Ticker: GRAL CUSIP: 384747101 Class: Common Stock

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 18,601 Value ($000) $1,592 Avg Close $86.40 Range $58.50 - $115.76

Q3 2025

Shares 16,501 Value ($000) $976 Avg Close $38.21 Range $29.95 - $59.70

Q2 2025

Shares 44,050 Value ($000) $2,265 Avg Close $36.20 Range $20.44 - $52.56

Q1 2025

Shares 113,950 Value ($000) $2,910 Avg Close $30.90 Range $16.56 - $63.99

Q4 2024

Shares 19,350 Value ($000) $345 Avg Close $16.26 Range $12.33 - $24.92

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	18,601	$1,592	$86.40	$58.50 - $115.76
Q3 2025	16,501	$976	$38.21	$29.95 - $59.70
Q2 2025	44,050	$2,265	$36.20	$20.44 - $52.56
Q1 2025	113,950	$2,910	$30.90	$16.56 - $63.99
Q4 2024	19,350	$345	$16.26	$12.33 - $24.92