IMPRIMIS PHARMACEUTICALS INC

CUSIP: 45323A201 Class: COMMON

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q1 2020
Shares 2,500,000 Value ($000) $9,550 Avg Close — Range —
Q4 2019
Shares 2,340,000 Value ($000) $18,205 Avg Close — Range —
Q3 2019
Shares 2,370,000 Value ($000) $13,319 Avg Close — Range —
Q2 2019
Shares 2,210,000 Value ($000) $19,227 Avg Close — Range —
Q1 2019
Shares 1,800,000 Value ($000) $8,964 Avg Close — Range —
Q4 2018
Shares 1,722,000 Value ($000) $9,798 Avg Close — Range —
Q3 2018
Shares 1,620,000 Value ($000) $4,503 Avg Close — Range —
Q2 2017
Shares 895,000 Value ($000) $2,864 Avg Close — Range —
Q1 2017
Shares 860,500 Value ($000) $3,588 Avg Close — Range —
Q4 2016
Shares 720,000 Value ($000) $1,800 Avg Close — Range —
Q3 2016
Shares 1,215,381 Value ($000) $4,631 Avg Close — Range —
Q2 2016
Shares 1,267,500 Value ($000) $4,766 Avg Close — Range —
Q1 2016
Shares 1,250,000 Value ($000) $4,963 Avg Close — Range —
Q4 2015
Shares 1,205,000 Value ($000) $8,351 Avg Close — Range —
Q3 2015
Shares 1,205,000 Value ($000) $7,736 Avg Close — Range —
Q2 2015
Shares 1,205,000 Value ($000) $9,797 Avg Close — Range —
Q1 2015
Shares 687,100 Value ($000) $5,490 Avg Close — Range —
Q4 2014
Shares 560,000 Value ($000) $4,200 Avg Close — Range —
Q3 2014
Shares 502,500 Value ($000) $3,728,550 Avg Close — Range —