INSMED INC

Ticker: INSM CUSIP: 457669307 Class: EQTY

D. E. Shaw & Co., Inc.'s Holding History (CIK: 0001009207)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 4,350,995 Value ($000) $757,247 Avg Close $182.48 Range $143.18 - $212.75

Q3 2025

Shares 5,657,464 Value ($000) $814,731 Avg Close $122.51 Range $95.01 - $149.08

Q2 2025

Shares 3,422,619 Value ($000) $344,452 Avg Close $76.46 Range $60.40 - $106.83

Q1 2025

Shares 734,880 Value ($000) $56,064 Avg Close $76.49 Range $61.50 - $84.91

Q4 2024

Shares 508,787 Value ($000) $35,127 Avg Close $72.02 Range $64.86 - $78.83

Q3 2024

Shares 66,735 Value ($000) $4,872 Avg Close $73.80 Range $61.52 - $80.53

Q2 2024

Shares 288,551 Value ($000) $19,333 Avg Close $38.78 Range $21.92 - $70.65

Q1 2024

Shares 174,022 Value ($000) $4,721 Avg Close $27.99 Range $25.06 - $31.14

Q4 2023

Shares 646,907 Value ($000) $20,048 Avg Close $25.93 Range $23.04 - $32.00

Q3 2023

Shares 196,727 Value ($000) $4,967 Avg Close $22.87 Range $19.74 - $27.59

Q2 2023

Shares 98,904 Value ($000) $2,087 Avg Close $18.97 Range $16.26 - $21.21

Q1 2023

Shares 237,367 Value ($000) $4,047 Avg Close $19.43 Range $16.04 - $22.23

Q4 2022

Shares 427,283 Value ($000) $8,537 Avg Close $19.33 Range $16.74 - $23.26

Q3 2022

Shares 636,993 Value ($000) $13,721 Avg Close $23.98 Range $19.58 - $28.94

Q2 2022

Shares 374,646 Value ($000) $7,388 Avg Close $20.95 Range $16.41 - $26.00

Q1 2022

Shares 295,993 Value ($000) $6,956 Avg Close $23.23 Range $20.02 - $28.74

Q4 2021

Shares 303,730 Value ($000) $8,274 Avg Close $28.59 Range $25.48 - $34.44

Q3 2021

Shares 363,984 Value ($000) $10,024 Avg Close $26.23 Range $22.00 - $29.55

Q2 2021

Shares 423,146 Value ($000) $12,043 Avg Close $29.68 Range $23.95 - $36.97

Q1 2021

Shares 749,809 Value ($000) $25,538 Avg Close $38.22 Range $31.69 - $45.44

Q4 2020

Shares 1,002,497 Value ($000) $33,373 Avg Close $36.53 Range $30.03 - $42.71

Q3 2020

Shares 1,615,050 Value ($000) $51,908 Avg Close $28.74 Range $25.21 - $35.32

Q2 2020

Shares 1,747,707 Value ($000) $48,132 Avg Close $23.71 Range $13.77 - $30.18

Q1 2020

Shares 2,236,848 Value ($000) $35,857 Avg Close $23.70 Range $12.09 - $34.94

Q4 2019

Shares 2,991,475 Value ($000) $71,437 Avg Close $20.34 Range $15.99 - $25.04

Q3 2019

Shares 2,561,306 Value ($000) $45,181 Avg Close $19.31 Range $15.33 - $26.25

Q2 2019

Shares 2,218,947 Value ($000) $56,805 Avg Close $27.86 Range $22.25 - $33.13

Q1 2019

Shares 593,566 Value ($000) $17,255 Avg Close $25.92 Range $12.85 - $31.50

Q4 2018

Shares 76,706 Value ($000) $1,006 Avg Close $15.96 Range $11.31 - $20.85

Q3 2018

Shares 148,115 Value ($000) $2,995 Avg Close $22.61 Range $18.64 - $31.58

Q2 2018

Shares 369,325 Value ($000) $8,735 Avg Close $25.74 Range $19.53 - $29.75

Q1 2018

Shares 293,978 Value ($000) $6,620 Avg Close $26.32 Range $21.38 - $33.94

Q4 2017

Shares 507,325 Value ($000) $15,818 Avg Close $29.54 Range $25.81 - $32.94

Q3 2017

Shares 813,562 Value ($000) $25,391 Avg Close $19.05 Range $11.49 - $31.39

Q2 2017

Shares 151,230 Value ($000) $2,595 Avg Close $17.08 Range $14.61 - $19.35

Q1 2017

Shares 156,005 Value ($000) $2,732 Avg Close $15.42 Range $12.74 - $17.51

Q4 2016

Shares 134,322 Value ($000) $1,777 Avg Close $13.64 Range $10.21 - $15.49

Q3 2016

Shares 134,382 Value ($000) $1,951 Avg Close $12.52 Range $9.75 - $15.35

Q2 2016

Shares 195,258 Value ($000) $1,925 Avg Close $11.67 Range $9.02 - $14.53

Q1 2016

Shares 122,819 Value ($000) $1,556 Avg Close $13.15 Range $10.53 - $18.60

Q4 2015

Shares 140,685 Value ($000) $2,553 Avg Close $17.62 Range $15.31 - $21.14

Q3 2015

Shares 308,012 Value ($000) $5,720 Avg Close $24.96 Range $17.07 - $28.66

Q2 2015

Shares 269,012 Value ($000) $6,570 Avg Close $22.70 Range $19.87 - $25.39

Q1 2015

Shares 128,575 Value ($000) $2,674 Avg Close $17.62 Range $13.93 - $22.59

Q4 2014

Shares 270,750 Value ($000) $4,188 Avg Close $14.19 Range $12.17 - $16.79

Q3 2014

Shares 25,170 Value ($000) $328 Avg Close $15.08 Range $11.25 - $20.33

Q2 2014

Shares 207,221 Value ($000) $4,140 Avg Close $14.81 Range $11.82 - $20.49

Q1 2014

Shares 77,217 Value ($000) $1,470 Avg Close $19.00 Range $15.55 - $22.29

Q4 2013

Shares 19,079 Value ($000) $325 Avg Close $15.31 Range $12.17 - $17.60

Q3 2013

Shares 29,074 Value ($000) $454 Avg Close $12.70 Range $9.00 - $16.50

Q2 2013

Shares 18,344 Value ($000) $219 Avg Close $10.22 Range $6.56 - $14.30

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	4,350,995	$757,247	$182.48	$143.18 - $212.75
Q3 2025	5,657,464	$814,731	$122.51	$95.01 - $149.08
Q2 2025	3,422,619	$344,452	$76.46	$60.40 - $106.83
Q1 2025	734,880	$56,064	$76.49	$61.50 - $84.91
Q4 2024	508,787	$35,127	$72.02	$64.86 - $78.83
Q3 2024	66,735	$4,872	$73.80	$61.52 - $80.53
Q2 2024	288,551	$19,333	$38.78	$21.92 - $70.65
Q1 2024	174,022	$4,721	$27.99	$25.06 - $31.14
Q4 2023	646,907	$20,048	$25.93	$23.04 - $32.00
Q3 2023	196,727	$4,967	$22.87	$19.74 - $27.59
Q2 2023	98,904	$2,087	$18.97	$16.26 - $21.21
Q1 2023	237,367	$4,047	$19.43	$16.04 - $22.23
Q4 2022	427,283	$8,537	$19.33	$16.74 - $23.26
Q3 2022	636,993	$13,721	$23.98	$19.58 - $28.94
Q2 2022	374,646	$7,388	$20.95	$16.41 - $26.00
Q1 2022	295,993	$6,956	$23.23	$20.02 - $28.74
Q4 2021	303,730	$8,274	$28.59	$25.48 - $34.44
Q3 2021	363,984	$10,024	$26.23	$22.00 - $29.55
Q2 2021	423,146	$12,043	$29.68	$23.95 - $36.97
Q1 2021	749,809	$25,538	$38.22	$31.69 - $45.44
Q4 2020	1,002,497	$33,373	$36.53	$30.03 - $42.71
Q3 2020	1,615,050	$51,908	$28.74	$25.21 - $35.32
Q2 2020	1,747,707	$48,132	$23.71	$13.77 - $30.18
Q1 2020	2,236,848	$35,857	$23.70	$12.09 - $34.94
Q4 2019	2,991,475	$71,437	$20.34	$15.99 - $25.04
Q3 2019	2,561,306	$45,181	$19.31	$15.33 - $26.25
Q2 2019	2,218,947	$56,805	$27.86	$22.25 - $33.13
Q1 2019	593,566	$17,255	$25.92	$12.85 - $31.50
Q4 2018	76,706	$1,006	$15.96	$11.31 - $20.85
Q3 2018	148,115	$2,995	$22.61	$18.64 - $31.58
Q2 2018	369,325	$8,735	$25.74	$19.53 - $29.75
Q1 2018	293,978	$6,620	$26.32	$21.38 - $33.94
Q4 2017	507,325	$15,818	$29.54	$25.81 - $32.94
Q3 2017	813,562	$25,391	$19.05	$11.49 - $31.39
Q2 2017	151,230	$2,595	$17.08	$14.61 - $19.35
Q1 2017	156,005	$2,732	$15.42	$12.74 - $17.51
Q4 2016	134,322	$1,777	$13.64	$10.21 - $15.49
Q3 2016	134,382	$1,951	$12.52	$9.75 - $15.35
Q2 2016	195,258	$1,925	$11.67	$9.02 - $14.53
Q1 2016	122,819	$1,556	$13.15	$10.53 - $18.60
Q4 2015	140,685	$2,553	$17.62	$15.31 - $21.14
Q3 2015	308,012	$5,720	$24.96	$17.07 - $28.66
Q2 2015	269,012	$6,570	$22.70	$19.87 - $25.39
Q1 2015	128,575	$2,674	$17.62	$13.93 - $22.59
Q4 2014	270,750	$4,188	$14.19	$12.17 - $16.79
Q3 2014	25,170	$328	$15.08	$11.25 - $20.33
Q2 2014	207,221	$4,140	$14.81	$11.82 - $20.49
Q1 2014	77,217	$1,470	$19.00	$15.55 - $22.29
Q4 2013	19,079	$325	$15.31	$12.17 - $17.60
Q3 2013	29,074	$454	$12.70	$9.00 - $16.50
Q2 2013	18,344	$219	$10.22	$6.56 - $14.30