INSMED INC

Ticker: INSM CUSIP: 457669307 Class: EQTY

CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM's Holding History (CIK: 0001081019)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 310,330 Value ($000) $54,010 Avg Close $182.48 Range $143.18 - $212.75

Q3 2025

Shares 179,402 Value ($000) $25,836 Avg Close $122.51 Range $95.01 - $149.08

Q2 2025

Shares 173,529 Value ($000) $17,464 Avg Close $76.46 Range $60.40 - $106.83

Q1 2025

Shares 157,698 Value ($000) $12,031 Avg Close $76.49 Range $61.50 - $84.91

Q4 2024

Shares 153,343 Value ($000) $10,587 Avg Close $72.02 Range $64.86 - $78.83

Q3 2024

Shares 146,742 Value ($000) $10,712 Avg Close $73.80 Range $61.52 - $80.53

Q2 2024

Shares 138,734 Value ($000) $9,295 Avg Close $38.78 Range $21.92 - $70.65

Q1 2024

Shares 136,107 Value ($000) $3,693 Avg Close $27.99 Range $25.06 - $31.14

Q4 2023

Shares 144,431 Value ($000) $4,476 Avg Close $25.93 Range $23.04 - $32.00

Q3 2023

Shares 149,734 Value ($000) $3,781 Avg Close $22.87 Range $19.74 - $27.59

Q2 2023

Shares 163,899 Value ($000) $3,458 Avg Close $18.97 Range $16.26 - $21.21

Q1 2023

Shares 169,310 Value ($000) $2,887 Avg Close $19.43 Range $16.04 - $22.23

Q4 2022

Shares 170,320 Value ($000) $3,403 Avg Close $19.33 Range $16.74 - $23.26

Q3 2022

Shares 149,929 Value ($000) $3,229 Avg Close $23.98 Range $19.58 - $28.94

Q2 2022

Shares 152,405 Value ($000) $3,005 Avg Close $20.95 Range $16.41 - $26.00

Q1 2022

Shares 152,296 Value ($000) $3,579 Avg Close $23.23 Range $20.02 - $28.74

Q4 2021

Shares 161,468 Value ($000) $4,398 Avg Close $28.59 Range $25.48 - $34.44

Q3 2021

Shares 155,005 Value ($000) $4,269 Avg Close $26.23 Range $22.00 - $29.55

Q2 2021

Shares 142,312 Value ($000) $4,050 Avg Close $29.68 Range $23.95 - $36.97

Q1 2021

Shares 152,668 Value ($000) $5,200 Avg Close $38.22 Range $31.69 - $45.44

Q4 2020

Shares 153,270 Value ($000) $5,102 Avg Close $36.53 Range $30.03 - $42.71

Q3 2020

Shares 153,263 Value ($000) $4,926 Avg Close $28.74 Range $25.21 - $35.32

Q2 2020

Shares 152,649 Value ($000) $4,204 Avg Close $23.71 Range $13.77 - $30.18

Q1 2020

Shares 135,338 Value ($000) $2,169 Avg Close $23.70 Range $12.09 - $34.94

Q4 2019

Shares 136,009 Value ($000) $3,248 Avg Close $20.34 Range $15.99 - $25.04

Q3 2019

Shares 138,756 Value ($000) $2,448 Avg Close $19.31 Range $15.33 - $26.25

Q2 2019

Shares 119,361 Value ($000) $3,056 Avg Close $27.86 Range $22.25 - $33.13

Q1 2019

Shares 117,253 Value ($000) $3,409 Avg Close $25.92 Range $12.85 - $31.50

Q4 2018

Shares 119,943 Value ($000) $1,574 Avg Close $15.96 Range $11.31 - $20.85

Q3 2018

Shares 117,158 Value ($000) $2,369 Avg Close $22.61 Range $18.64 - $31.58

Q2 2018

Shares 117,199 Value ($000) $2,772 Avg Close $25.74 Range $19.53 - $29.75

Q1 2018

Shares 116,525 Value ($000) $2,624 Avg Close $26.32 Range $21.38 - $33.94

Q4 2017

Shares 120,610 Value ($000) $3,761 Avg Close $29.54 Range $25.81 - $32.94

Q3 2017

Shares 118,925 Value ($000) $3,712 Avg Close $19.05 Range $11.49 - $31.39

Q2 2017

Shares 109,920 Value ($000) $1,886 Avg Close $17.08 Range $14.61 - $19.35

Q1 2017

Shares 121,948 Value ($000) $2,135 Avg Close $15.42 Range $12.74 - $17.51

Q4 2016

Shares 127,548 Value ($000) $1,687 Avg Close $13.64 Range $10.21 - $15.49

Q3 2016

Shares 131,048 Value ($000) $1,903 Avg Close $12.52 Range $9.75 - $15.35

Q2 2016

Shares 129,848 Value ($000) $1,280 Avg Close $11.67 Range $9.02 - $14.53

Q1 2016

Shares 130,313 Value ($000) $1,651 Avg Close $13.15 Range $10.53 - $18.60

Q4 2015

Shares 113,929 Value ($000) $2,068 Avg Close $17.62 Range $15.31 - $21.14

Q3 2015

Shares 112,125 Value ($000) $2,082 Avg Close $24.96 Range $17.07 - $28.66

Q2 2015

Shares 112,325 Value ($000) $2,743 Avg Close $22.70 Range $19.87 - $25.39

Q1 2015

Shares 90,329 Value ($000) $1,879 Avg Close $17.62 Range $13.93 - $22.59

Q4 2014

Shares 91,929 Value ($000) $1,422 Avg Close $14.19 Range $12.17 - $16.79

Q3 2014

Shares 91,538 Value ($000) $1,195 Avg Close $15.08 Range $11.25 - $20.33

Q2 2014

Shares 71,726 Value ($000) $1,433 Avg Close $14.81 Range $11.82 - $20.49

Q1 2014

Shares 62,626 Value ($000) $1,192 Avg Close $19.00 Range $15.55 - $22.29

Q4 2013

Shares 62,626 Value ($000) $1,065 Avg Close $15.31 Range $12.17 - $17.60

Q3 2013

Shares 61,926 Value ($000) $967 Avg Close $12.70 Range $9.00 - $16.50

Q2 2013

Shares 49,226 Value ($000) $589 Avg Close $10.22 Range $6.56 - $14.30

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	310,330	$54,010	$182.48	$143.18 - $212.75
Q3 2025	179,402	$25,836	$122.51	$95.01 - $149.08
Q2 2025	173,529	$17,464	$76.46	$60.40 - $106.83
Q1 2025	157,698	$12,031	$76.49	$61.50 - $84.91
Q4 2024	153,343	$10,587	$72.02	$64.86 - $78.83
Q3 2024	146,742	$10,712	$73.80	$61.52 - $80.53
Q2 2024	138,734	$9,295	$38.78	$21.92 - $70.65
Q1 2024	136,107	$3,693	$27.99	$25.06 - $31.14
Q4 2023	144,431	$4,476	$25.93	$23.04 - $32.00
Q3 2023	149,734	$3,781	$22.87	$19.74 - $27.59
Q2 2023	163,899	$3,458	$18.97	$16.26 - $21.21
Q1 2023	169,310	$2,887	$19.43	$16.04 - $22.23
Q4 2022	170,320	$3,403	$19.33	$16.74 - $23.26
Q3 2022	149,929	$3,229	$23.98	$19.58 - $28.94
Q2 2022	152,405	$3,005	$20.95	$16.41 - $26.00
Q1 2022	152,296	$3,579	$23.23	$20.02 - $28.74
Q4 2021	161,468	$4,398	$28.59	$25.48 - $34.44
Q3 2021	155,005	$4,269	$26.23	$22.00 - $29.55
Q2 2021	142,312	$4,050	$29.68	$23.95 - $36.97
Q1 2021	152,668	$5,200	$38.22	$31.69 - $45.44
Q4 2020	153,270	$5,102	$36.53	$30.03 - $42.71
Q3 2020	153,263	$4,926	$28.74	$25.21 - $35.32
Q2 2020	152,649	$4,204	$23.71	$13.77 - $30.18
Q1 2020	135,338	$2,169	$23.70	$12.09 - $34.94
Q4 2019	136,009	$3,248	$20.34	$15.99 - $25.04
Q3 2019	138,756	$2,448	$19.31	$15.33 - $26.25
Q2 2019	119,361	$3,056	$27.86	$22.25 - $33.13
Q1 2019	117,253	$3,409	$25.92	$12.85 - $31.50
Q4 2018	119,943	$1,574	$15.96	$11.31 - $20.85
Q3 2018	117,158	$2,369	$22.61	$18.64 - $31.58
Q2 2018	117,199	$2,772	$25.74	$19.53 - $29.75
Q1 2018	116,525	$2,624	$26.32	$21.38 - $33.94
Q4 2017	120,610	$3,761	$29.54	$25.81 - $32.94
Q3 2017	118,925	$3,712	$19.05	$11.49 - $31.39
Q2 2017	109,920	$1,886	$17.08	$14.61 - $19.35
Q1 2017	121,948	$2,135	$15.42	$12.74 - $17.51
Q4 2016	127,548	$1,687	$13.64	$10.21 - $15.49
Q3 2016	131,048	$1,903	$12.52	$9.75 - $15.35
Q2 2016	129,848	$1,280	$11.67	$9.02 - $14.53
Q1 2016	130,313	$1,651	$13.15	$10.53 - $18.60
Q4 2015	113,929	$2,068	$17.62	$15.31 - $21.14
Q3 2015	112,125	$2,082	$24.96	$17.07 - $28.66
Q2 2015	112,325	$2,743	$22.70	$19.87 - $25.39
Q1 2015	90,329	$1,879	$17.62	$13.93 - $22.59
Q4 2014	91,929	$1,422	$14.19	$12.17 - $16.79
Q3 2014	91,538	$1,195	$15.08	$11.25 - $20.33
Q2 2014	71,726	$1,433	$14.81	$11.82 - $20.49
Q1 2014	62,626	$1,192	$19.00	$15.55 - $22.29
Q4 2013	62,626	$1,065	$15.31	$12.17 - $17.60
Q3 2013	61,926	$967	$12.70	$9.00 - $16.50
Q2 2013	49,226	$589	$10.22	$6.56 - $14.30