INSMED INC

Ticker: INSM CUSIP: 457669307 Class: EQTY

Nuveen, LLC's Holding History (CIK: 0001871926)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 650,404 Value ($000) $113,196 Avg Close $182.48 Range $143.18 - $212.75

Q3 2025

Shares 588,122 Value ($000) $84,695 Avg Close $122.51 Range $95.01 - $149.08

Q2 2025

Shares 588,987 Value ($000) $59,276 Avg Close $76.46 Range $60.40 - $106.83

Q1 2025

Shares 1,158,094 Value ($000) $88,351 Avg Close $76.49 Range $61.50 - $84.91

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	650,404	$113,196	$182.48	$143.18 - $212.75
Q3 2025	588,122	$84,695	$122.51	$95.01 - $149.08
Q2 2025	588,987	$59,276	$76.46	$60.40 - $106.83
Q1 2025	1,158,094	$88,351	$76.49	$61.50 - $84.91