INSPIRE MED SYS INC

Ticker: INSP CUSIP: 457730109 Class: Common Stock

WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC's Holding History (CIK: 0001644956)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,161,285 Value ($000) $107,105 Avg Close $95.68 Range $70.77 - $147.03

Q3 2025

Shares 1,297,573 Value ($000) $96,280 Avg Close $101.25 Range $72.66 - $143.96

Q2 2025

Shares 769,169 Value ($000) $99,815 Avg Close $145.01 Range $125.22 - $164.02

Q1 2025

Shares 692,918 Value ($000) $110,368 Avg Close $180.91 Range $151.82 - $216.01

Q4 2024

Shares 902,611 Value ($000) $167,326 Avg Close $194.11 Range $170.23 - $214.97

Q3 2024

Shares 906,349 Value ($000) $191,285 Avg Close $173.72 Range $123.00 - $225.00

Q2 2024

Shares 770,413 Value ($000) $103,104 Avg Close $189.24 Range $129.95 - $257.40

Q1 2024

Shares 756,811 Value ($000) $162,555 Avg Close $196.02 Range $163.57 - $226.38

Q4 2023

Shares 806,947 Value ($000) $164,157 Avg Close $162.01 Range $123.27 - $206.88

Q3 2023

Shares 694,145 Value ($000) $137,746 Avg Close $252.20 Range $183.10 - $330.00

Q2 2023

Shares 836,162 Value ($000) $271,452 Avg Close $285.71 Range $223.21 - $327.77

Q1 2023

Shares 836,690 Value ($000) $195,844 Avg Close $252.78 Range $224.42 - $282.31

Q4 2022

Shares 833,423 Value ($000) $209,923 Avg Close $213.22 Range $159.62 - $262.54

Q3 2022

Shares 658,612 Value ($000) $116,818 Avg Close $200.95 Range $164.49 - $231.41

Q2 2022

Shares 664,391 Value ($000) $121,364 Avg Close $199.42 Range $142.74 - $272.04

Q1 2022

Shares 754,085 Value ($000) $193,566 Avg Close $228.53 Range $189.24 - $263.83

Q4 2021

Shares 884,191 Value ($000) $203,417 Avg Close $244.16 Range $198.00 - $286.29

Q3 2021

Shares 895,976 Value ($000) $208,655 Avg Close $208.67 Range $159.18 - $264.40

Q2 2021

Shares 761,475 Value ($000) $147,163 Avg Close $198.33 Range $160.02 - $244.89

Q1 2021

Shares 643,181 Value ($000) $133,132 Avg Close $212.51 Range $179.62 - $252.25

Q4 2020

Shares 528,081 Value ($000) $99,327 Avg Close $163.50 Range $115.00 - $204.72

Q4 2019

Shares 1,190,766 Value ($000) $88,367 Avg Close $64.28 Range $51.98 - $75.91

Q3 2019

Shares 1,118,100 Value ($000) $68,226 Avg Close $65.85 Range $58.56 - $71.71

Q2 2019

Shares 1,160,880 Value ($000) $70,407 Avg Close $53.90 Range $46.00 - $61.45

Q1 2019

Shares 1,096,095 Value ($000) $62,236 Avg Close $54.03 Range $38.68 - $64.34

Q4 2018

Shares 212,269 Value ($000) $8,968 Avg Close $42.52 Range $35.43 - $54.51

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,161,285	$107,105	$95.68	$70.77 - $147.03
Q3 2025	1,297,573	$96,280	$101.25	$72.66 - $143.96
Q2 2025	769,169	$99,815	$145.01	$125.22 - $164.02
Q1 2025	692,918	$110,368	$180.91	$151.82 - $216.01
Q4 2024	902,611	$167,326	$194.11	$170.23 - $214.97
Q3 2024	906,349	$191,285	$173.72	$123.00 - $225.00
Q2 2024	770,413	$103,104	$189.24	$129.95 - $257.40
Q1 2024	756,811	$162,555	$196.02	$163.57 - $226.38
Q4 2023	806,947	$164,157	$162.01	$123.27 - $206.88
Q3 2023	694,145	$137,746	$252.20	$183.10 - $330.00
Q2 2023	836,162	$271,452	$285.71	$223.21 - $327.77
Q1 2023	836,690	$195,844	$252.78	$224.42 - $282.31
Q4 2022	833,423	$209,923	$213.22	$159.62 - $262.54
Q3 2022	658,612	$116,818	$200.95	$164.49 - $231.41
Q2 2022	664,391	$121,364	$199.42	$142.74 - $272.04
Q1 2022	754,085	$193,566	$228.53	$189.24 - $263.83
Q4 2021	884,191	$203,417	$244.16	$198.00 - $286.29
Q3 2021	895,976	$208,655	$208.67	$159.18 - $264.40
Q2 2021	761,475	$147,163	$198.33	$160.02 - $244.89
Q1 2021	643,181	$133,132	$212.51	$179.62 - $252.25
Q4 2020	528,081	$99,327	$163.50	$115.00 - $204.72
Q4 2019	1,190,766	$88,367	$64.28	$51.98 - $75.91
Q3 2019	1,118,100	$68,226	$65.85	$58.56 - $71.71
Q2 2019	1,160,880	$70,407	$53.90	$46.00 - $61.45
Q1 2019	1,096,095	$62,236	$54.03	$38.68 - $64.34
Q4 2018	212,269	$8,968	$42.52	$35.43 - $54.51