IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Commonwealth Bank of Australia's Holding History (CIK: 0000008565)

Note: Option positions (PUT/CALL) are excluded.

Q3 2016

Shares 600 Value ($000) $22 Avg Close $31.29 Range $23.26 - $40.82

Q2 2016

Shares 600 Value ($000) $14 Avg Close $32.26 Range $19.59 - $46.75

Q1 2016

Shares 600 Value ($000) $24 Avg Close $40.62 Range $30.93 - $62.68

Q4 2015

Shares 300 Value ($000) $19 Avg Close $53.96 Range $38.30 - $65.34

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2016	600	$22	$31.29	$23.26 - $40.82
Q2 2016	600	$14	$32.26	$19.59 - $46.75
Q1 2016	600	$24	$40.62	$30.93 - $62.68
Q4 2015	300	$19	$53.96	$38.30 - $65.34