IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Virtus Investment Advisers, LLC's Holding History (CIK: 0000019481)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 8,454 Value ($000) $669 Avg Close $75.30 Range $64.93 - $83.61

Q3 2025

Shares 12,476 Value ($000) $816 Avg Close $48.82 Range $39.72 - $65.55

Q2 2025

Shares 12,476 Value ($000) $493 Avg Close $32.73 Range $23.95 - $40.61

Q1 2025

Shares 9,701 Value ($000) $293 Avg Close $32.75 Range $29.61 - $35.48

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	8,454	$669	$75.30	$64.93 - $83.61
Q3 2025	12,476	$816	$48.82	$39.72 - $65.55
Q2 2025	12,476	$493	$32.73	$23.95 - $40.61
Q1 2025	9,701	$293	$32.75	$29.61 - $35.48