IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Tweedy, Browne Co LLC's Holding History (CIK: 0000732905)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025
Shares 2,464,930 Value ($000) $195,001 Avg Close $75.30 Range $64.93 - $83.61
Q3 2025
Shares 2,901,216 Value ($000) $189,798 Avg Close $48.82 Range $39.72 - $65.55
Q2 2025
Shares 2,891,948 Value ($000) $114,261 Avg Close $32.73 Range $23.95 - $40.61
Q1 2025
Shares 2,983,518 Value ($000) $90,013 Avg Close $32.75 Range $29.61 - $35.48
Q4 2024
Shares 3,248,863 Value ($000) $113,580 Avg Close $37.38 Range $33.33 - $40.58
Q3 2024
Shares 3,454,676 Value ($000) $138,394 Avg Close $46.53 Range $39.48 - $52.34
Q2 2024
Shares 3,454,676 Value ($000) $164,650 Avg Close $41.01 Range $35.95 - $47.86
Q1 2024
Shares 3,454,676 Value ($000) $149,760 Avg Close $47.67 Range $41.60 - $54.44
Q4 2023
Shares 3,454,676 Value ($000) $174,772 Avg Close $47.90 Range $41.84 - $52.27
Q3 2023
Shares 3,510,173 Value ($000) $159,221 Avg Close $41.26 Range $38.26 - $47.72
Q2 2023
Shares 3,540,858 Value ($000) $145 Avg Close $38.43 Range $34.32 - $43.55
Q1 2023
Shares 3,541,046 Value ($000) $127 Avg Close $37.55 Range $32.69 - $41.73
Q4 2022
Shares 3,541,136 Value ($000) $134 Avg Close $42.06 Range $36.69 - $47.74
Q3 2022
Shares 2,722,988 Value ($000) $120,438 Avg Close $42.14 Range $35.95 - $48.82
Q2 2022
Shares 2,726,778 Value ($000) $100,945 Avg Close $37.71 Range $31.46 - $44.42
Q1 2022
Shares 2,925,102 Value ($000) $108,346 Avg Close $32.73 Range $28.25 - $37.15