IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

FIRST HAWAIIAN BANK's Holding History (CIK: 0000764106)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019

Shares 1,174 Value ($000) $95 Avg Close $64.51 Range $52.45 - $81.59

Q4 2018

Shares 1,512 Value ($000) $81 Avg Close $51.00 Range $43.27 - $59.81

Q3 2018

Shares 1,917 Value ($000) $99 Avg Close $46.98 Range $41.05 - $54.85

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2019	1,174	$95	$64.51	$52.45 - $81.59
Q4 2018	1,512	$81	$51.00	$43.27 - $59.81
Q3 2018	1,917	$99	$46.98	$41.05 - $54.85