IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

NATIONAL BANK OF CANADA /FI/'s Holding History (CIK: 0000926171)

Note: Option positions (PUT/CALL) are excluded.

Q2 2024

Shares 80 Value ($000) $4 Avg Close $41.01 Range $35.95 - $47.86

Q1 2024

Shares 80 Value ($000) $3 Avg Close $47.67 Range $41.60 - $54.44

Q4 2022

Shares 60,895 Value ($000) $2,299 Avg Close $42.06 Range $36.69 - $47.74

Q3 2022

Shares 51,720 Value ($000) $2,287 Avg Close $42.14 Range $35.95 - $48.82

Q4 2021

Shares 70,000 Value ($000) $2,130 Avg Close $31.48 Range $25.04 - $35.80

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2024	80	$4	$41.01	$35.95 - $47.86
Q1 2024	80	$3	$47.67	$41.60 - $54.44
Q4 2022	60,895	$2,299	$42.06	$36.69 - $47.74
Q3 2022	51,720	$2,287	$42.14	$35.95 - $48.82
Q4 2021	70,000	$2,130	$31.48	$25.04 - $35.80