IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

BROOKFIELD Corp /ON/'s Holding History (CIK: 0001001085)

Note: Option positions (PUT/CALL) are excluded.

Q4 2021

Shares 9,638 Value ($000) $293 Avg Close $31.48 Range $25.04 - $35.80

Q2 2021

Shares 13,568 Value ($000) $541 Avg Close $39.17 Range $34.43 - $47.87

Q4 2020

Shares 18,513 Value ($000) $1,047 Avg Close $49.83 Range $45.09 - $60.95

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2021	9,638	$293	$31.48	$25.04 - $35.80
Q2 2021	13,568	$541	$39.17	$34.43 - $47.87
Q4 2020	18,513	$1,047	$49.83	$45.09 - $60.95