IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

EMERALD ADVISERS, LLC's Holding History (CIK: 0001015083)

Note: Option positions (PUT/CALL) are excluded.

Q3 2021

Shares 16,815 Value ($000) $564 Avg Close $37.68 Range $33.52 - $40.99

Q2 2021

Shares 17,621 Value ($000) $703 Avg Close $39.17 Range $34.43 - $47.87

Q1 2021

Shares 17,621 Value ($000) $792 Avg Close $55.77 Range $41.42 - $64.37

Q3 2017

Shares 22,132 Value ($000) $1,122 Avg Close $52.38 Range $43.75 - $60.01

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2021	16,815	$564	$37.68	$33.52 - $40.99
Q2 2021	17,621	$703	$39.17	$34.43 - $47.87
Q1 2021	17,621	$792	$55.77	$41.42 - $64.37
Q3 2017	22,132	$1,122	$52.38	$43.75 - $60.01