IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

VICTORY CAPITAL MANAGEMENT INC's Holding History (CIK: 0001040188)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 80,729 Value ($000) $6,386 Avg Close $75.30 Range $64.93 - $83.61

Q3 2025

Shares 18,211 Value ($000) $1,191 Avg Close $48.82 Range $39.72 - $65.55

Q2 2025

Shares 18,516 Value ($000) $732 Avg Close $32.73 Range $23.95 - $40.61

Q1 2025

Shares 18,641 Value ($000) $562 Avg Close $32.75 Range $29.61 - $35.48

Q4 2024

Shares 18,004 Value ($000) $629 Avg Close $37.38 Range $33.33 - $40.58

Q3 2024

Shares 18,350 Value ($000) $735 Avg Close $46.53 Range $39.48 - $52.34

Q2 2024

Shares 17,330 Value ($000) $826 Avg Close $41.01 Range $35.95 - $47.86

Q1 2024

Shares 17,637 Value ($000) $765 Avg Close $47.67 Range $41.60 - $54.44

Q4 2023

Shares 27,793 Value ($000) $1,406 Avg Close $47.90 Range $41.84 - $52.27

Q3 2023

Shares 15,436 Value ($000) $700 Avg Close $41.26 Range $38.26 - $47.72

Q2 2023

Shares 15,088 Value ($000) $619 Avg Close $38.43 Range $34.32 - $43.55

Q1 2023

Shares 15,439 Value ($000) $552 Avg Close $37.55 Range $32.69 - $41.73

Q4 2022

Shares 15,787 Value ($000) $596 Avg Close $42.06 Range $36.69 - $47.74

Q3 2022

Shares 15,795 Value ($000) $699 Avg Close $42.14 Range $35.95 - $48.82

Q2 2022

Shares 13,546 Value ($000) $501 Avg Close $37.71 Range $31.46 - $44.42

Q1 2022

Shares 11,825 Value ($000) $435 Avg Close $32.73 Range $28.25 - $37.15

Q4 2021

Shares 13,147 Value ($000) $400 Avg Close $31.48 Range $25.04 - $35.80

Q3 2021

Shares 13,339 Value ($000) $447 Avg Close $37.68 Range $33.52 - $40.99

Q2 2021

Shares 14,216 Value ($000) $567 Avg Close $39.17 Range $34.43 - $47.87

Q1 2021

Shares 26,250 Value ($000) $1,180 Avg Close $55.77 Range $41.42 - $64.37

Q4 2020

Shares 85,290 Value ($000) $4,822 Avg Close $49.83 Range $45.09 - $60.95

Q3 2020

Shares 73,737 Value ($000) $3,499 Avg Close $55.55 Range $47.19 - $63.49

Q2 2020

Shares 17,100 Value ($000) $1,008 Avg Close $55.63 Range $45.12 - $61.24

Q1 2020

Shares 17,737 Value ($000) $839 Avg Close $55.74 Range $39.32 - $64.34

Q4 2019

Shares 15,871 Value ($000) $959 Avg Close $59.58 Range $53.34 - $66.22

Q3 2019

Shares 16,424 Value ($000) $984 Avg Close $65.17 Range $58.48 - $73.09

Q2 2017

Shares 591 Value ($000) $30 Avg Close $46.57 Range $37.26 - $55.73

Q1 2017

Shares 581 Value ($000) $23 Avg Close $44.91 Range $37.29 - $56.91

Q4 2016

Shares 454 Value ($000) $22 Avg Close $39.57 Range $24.58 - $57.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	80,729	$6,386	$75.30	$64.93 - $83.61
Q3 2025	18,211	$1,191	$48.82	$39.72 - $65.55
Q2 2025	18,516	$732	$32.73	$23.95 - $40.61
Q1 2025	18,641	$562	$32.75	$29.61 - $35.48
Q4 2024	18,004	$629	$37.38	$33.33 - $40.58
Q3 2024	18,350	$735	$46.53	$39.48 - $52.34
Q2 2024	17,330	$826	$41.01	$35.95 - $47.86
Q1 2024	17,637	$765	$47.67	$41.60 - $54.44
Q4 2023	27,793	$1,406	$47.90	$41.84 - $52.27
Q3 2023	15,436	$700	$41.26	$38.26 - $47.72
Q2 2023	15,088	$619	$38.43	$34.32 - $43.55
Q1 2023	15,439	$552	$37.55	$32.69 - $41.73
Q4 2022	15,787	$596	$42.06	$36.69 - $47.74
Q3 2022	15,795	$699	$42.14	$35.95 - $48.82
Q2 2022	13,546	$501	$37.71	$31.46 - $44.42
Q1 2022	11,825	$435	$32.73	$28.25 - $37.15
Q4 2021	13,147	$400	$31.48	$25.04 - $35.80
Q3 2021	13,339	$447	$37.68	$33.52 - $40.99
Q2 2021	14,216	$567	$39.17	$34.43 - $47.87
Q1 2021	26,250	$1,180	$55.77	$41.42 - $64.37
Q4 2020	85,290	$4,822	$49.83	$45.09 - $60.95
Q3 2020	73,737	$3,499	$55.55	$47.19 - $63.49
Q2 2020	17,100	$1,008	$55.63	$45.12 - $61.24
Q1 2020	17,737	$839	$55.74	$39.32 - $64.34
Q4 2019	15,871	$959	$59.58	$53.34 - $66.22
Q3 2019	16,424	$984	$65.17	$58.48 - $73.09
Q2 2017	591	$30	$46.57	$37.26 - $55.73
Q1 2017	581	$23	$44.91	$37.29 - $56.91
Q4 2016	454	$22	$39.57	$24.58 - $57.00