IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

INTECH INVESTMENT MANAGEMENT LLC's Holding History (CIK: 0001086318)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 9,602 Value ($000) $760 Avg Close $75.30 Range $64.93 - $83.61

Q1 2025

Shares 12,207 Value ($000) $368 Avg Close $32.75 Range $29.61 - $35.48

Q4 2022

Shares 50,510 Value ($000) $1,908 Avg Close $42.06 Range $36.69 - $47.74

Q3 2022

Shares 57,140 Value ($000) $2,527 Avg Close $42.14 Range $35.95 - $48.82

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	9,602	$760	$75.30	$64.93 - $83.61
Q1 2025	12,207	$368	$32.75	$29.61 - $35.48
Q4 2022	50,510	$1,908	$42.06	$36.69 - $47.74
Q3 2022	57,140	$2,527	$42.14	$35.95 - $48.82