IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Nationwide Fund Advisors's Holding History (CIK: 0001097218)

Note: Option positions (PUT/CALL) are excluded.

Q3 2017

Shares 76,457 Value ($000) $3,876 Avg Close $52.38 Range $43.75 - $60.01

Q2 2017

Shares 76,457 Value ($000) $3,889 Avg Close $46.57 Range $37.26 - $55.73

Q1 2017

Shares 18,505 Value ($000) $744 Avg Close $44.91 Range $37.29 - $56.91

Q4 2016

Shares 18,505 Value ($000) $885 Avg Close $39.57 Range $24.58 - $57.00

Q3 2016

Shares 20,885 Value ($000) $765 Avg Close $31.29 Range $23.26 - $40.82

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2017	76,457	$3,876	$52.38	$43.75 - $60.01
Q2 2017	76,457	$3,889	$46.57	$37.26 - $55.73
Q1 2017	18,505	$744	$44.91	$37.29 - $56.91
Q4 2016	18,505	$885	$39.57	$24.58 - $57.00
Q3 2016	20,885	$765	$31.29	$23.26 - $40.82