IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

ADVENT CAPITAL MANAGEMENT /DE/'s Holding History (CIK: 0001097278)

Note: Option positions (PUT/CALL) are excluded.

Q3 2024

Shares 10,000 Value ($000) $401 Avg Close $46.53 Range $39.48 - $52.34

Q1 2023

Shares 464 Value ($000) $17 Avg Close $37.55 Range $32.69 - $41.73

Q4 2022

Shares 464 Value ($000) $18 Avg Close $42.06 Range $36.69 - $47.74

Q3 2022

Shares 464 Value ($000) $21 Avg Close $42.14 Range $35.95 - $48.82

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2024	10,000	$401	$46.53	$39.48 - $52.34
Q1 2023	464	$17	$37.55	$32.69 - $41.73
Q4 2022	464	$18	$42.06	$36.69 - $47.74
Q3 2022	464	$21	$42.14	$35.95 - $48.82