IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

LOGAN CAPITAL MANAGEMENT INC's Holding History (CIK: 0001121330)

Note: Option positions (PUT/CALL) are excluded.

Q4 2021

Shares 178 Value ($000) $5 Avg Close $31.48 Range $25.04 - $35.80

Q3 2021

Shares 178 Value ($000) $6 Avg Close $37.68 Range $33.52 - $40.99

Q2 2021

Shares 178 Value ($000) $7 Avg Close $39.17 Range $34.43 - $47.87

Q1 2021

Shares 178 Value ($000) $8 Avg Close $55.77 Range $41.42 - $64.37

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2021	178	$5	$31.48	$25.04 - $35.80
Q3 2021	178	$6	$37.68	$33.52 - $40.99
Q2 2021	178	$7	$39.17	$34.43 - $47.87
Q1 2021	178	$8	$55.77	$41.42 - $64.37