IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Curi Capital, LLC's Holding History (CIK: 0001332905)

Note: Option positions (PUT/CALL) are excluded.

Q3 2019

Shares 13,178 Value ($000) $789 Avg Close $65.17 Range $58.48 - $73.09

Q2 2019

Shares 20,886 Value ($000) $1,342 Avg Close $70.69 Range $61.91 - $86.58

Q1 2019

Shares 31,028 Value ($000) $2,519 Avg Close $64.51 Range $52.45 - $81.59

Q4 2018

Shares 31,028 Value ($000) $1,677 Avg Close $51.00 Range $43.27 - $59.81

Q3 2018

Shares 36,035 Value ($000) $1,859 Avg Close $46.98 Range $41.05 - $54.85

Q2 2018

Shares 38,538 Value ($000) $1,606 Avg Close $44.30 Range $39.07 - $51.00

Q1 2018

Shares 53,488 Value ($000) $2,358 Avg Close $50.80 Range $43.38 - $56.47

Q4 2017

Shares 66,842 Value ($000) $3,362 Avg Close $54.84 Range $50.02 - $65.51

Q3 2017

Shares 82,635 Value ($000) $4,190 Avg Close $52.38 Range $43.75 - $60.01

Q2 2017

Shares 83,105 Value ($000) $4,228 Avg Close $46.57 Range $37.26 - $55.73

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2019	13,178	$789	$65.17	$58.48 - $73.09
Q2 2019	20,886	$1,342	$70.69	$61.91 - $86.58
Q1 2019	31,028	$2,519	$64.51	$52.45 - $81.59
Q4 2018	31,028	$1,677	$51.00	$43.27 - $59.81
Q3 2018	36,035	$1,859	$46.98	$41.05 - $54.85
Q2 2018	38,538	$1,606	$44.30	$39.07 - $51.00
Q1 2018	53,488	$2,358	$50.80	$43.38 - $56.47
Q4 2017	66,842	$3,362	$54.84	$50.02 - $65.51
Q3 2017	82,635	$4,190	$52.38	$43.75 - $60.01
Q2 2017	83,105	$4,228	$46.57	$37.26 - $55.73