IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Bridgewater Associates, LP's Holding History (CIK: 0001350694)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 67,706 Value ($000) $5,356 Avg Close $75.30 Range $64.93 - $83.61

Q3 2025

Shares 43,578 Value ($000) $2,851 Avg Close $48.82 Range $39.72 - $65.55

Q2 2022

Shares 9,779 Value ($000) $362 Avg Close $37.71 Range $31.46 - $44.42

Q1 2022

Shares 7,201 Value ($000) $267 Avg Close $32.73 Range $28.25 - $37.15

Q2 2021

Shares 7,981 Value ($000) $318 Avg Close $39.17 Range $34.43 - $47.87

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	67,706	$5,356	$75.30	$64.93 - $83.61
Q3 2025	43,578	$2,851	$48.82	$39.72 - $65.55
Q2 2022	9,779	$362	$37.71	$31.46 - $44.42
Q1 2022	7,201	$267	$32.73	$28.25 - $37.15
Q2 2021	7,981	$318	$39.17	$34.43 - $47.87