IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Brinker Capital Investments, LLC's Holding History (CIK: 0001360533)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 23,574 Value ($000) $1,865 Avg Close $75.30 Range $64.93 - $83.61

Q3 2025

Shares 9,962 Value ($000) $652 Avg Close $48.82 Range $39.72 - $65.55

Q2 2025

Shares 5,600 Value ($000) $221 Avg Close $32.73 Range $23.95 - $40.61

Q4 2019

Shares 138 Value ($000) $8 Avg Close $59.58 Range $53.34 - $66.22

Q3 2019

Shares 138 Value ($000) $8 Avg Close $65.17 Range $58.48 - $73.09

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	23,574	$1,865	$75.30	$64.93 - $83.61
Q3 2025	9,962	$652	$48.82	$39.72 - $65.55
Q2 2025	5,600	$221	$32.73	$23.95 - $40.61
Q4 2019	138	$8	$59.58	$53.34 - $66.22
Q3 2019	138	$8	$65.17	$58.48 - $73.09