IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

CAPSTONE INVESTMENT ADVISORS, LLC's Holding History (CIK: 0001426196)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 10,402 Value ($000) $680 Avg Close $48.82 Range $39.72 - $65.55

Q1 2017

Shares 13,426 Value ($000) $539 Avg Close $44.91 Range $37.29 - $56.91

Q4 2016

Shares 32,614 Value ($000) $1,559 Avg Close $39.57 Range $24.58 - $57.00

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	10,402	$680	$48.82	$39.72 - $65.55
Q1 2017	13,426	$539	$44.91	$37.29 - $56.91
Q4 2016	32,614	$1,559	$39.57	$24.58 - $57.00