IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Legato Capital Management LLC's Holding History (CIK: 0001442641)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 6,155 Value ($000) $487 Avg Close $75.30 Range $64.93 - $83.61

Q3 2025

Shares 17,300 Value ($000) $1,132 Avg Close $48.82 Range $39.72 - $65.55

Q4 2023

Shares 5,455 Value ($000) $276 Avg Close $47.90 Range $41.84 - $52.27

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	6,155	$487	$75.30	$64.93 - $83.61
Q3 2025	17,300	$1,132	$48.82	$39.72 - $65.55
Q4 2023	5,455	$276	$47.90	$41.84 - $52.27