IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

NEUBERGER BERMAN GROUP LLC's Holding History (CIK: 0001465109)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 108,044 Value ($000) $8,547 Avg Close $75.30 Range $64.93 - $83.61

Q3 2025

Shares 114,743 Value ($000) $7,506 Avg Close $48.82 Range $39.72 - $65.55

Q2 2025

Shares 114,623 Value ($000) $4,529 Avg Close $32.73 Range $23.95 - $40.61

Q1 2025

Shares 102,473 Value ($000) $3,092 Avg Close $32.75 Range $29.61 - $35.48

Q4 2024

Shares 96,631 Value ($000) $3,378 Avg Close $37.38 Range $33.33 - $40.58

Q3 2024

Shares 64,874 Value ($000) $2,599 Avg Close $46.53 Range $39.48 - $52.34

Q2 2024

Shares 14,312 Value ($000) $682 Avg Close $41.01 Range $35.95 - $47.86

Q1 2024

Shares 14,234 Value ($000) $617 Avg Close $47.67 Range $41.60 - $54.44

Q4 2023

Shares 13,998 Value ($000) $708 Avg Close $47.90 Range $41.84 - $52.27

Q3 2023

Shares 15,534 Value ($000) $705 Avg Close $41.26 Range $38.26 - $47.72

Q2 2023

Shares 15,206 Value ($000) $624 Avg Close $38.43 Range $34.32 - $43.55

Q1 2023

Shares 15,132 Value ($000) $541 Avg Close $37.55 Range $32.69 - $41.73

Q4 2022

Shares 10,985 Value ($000) $415 Avg Close $42.06 Range $36.69 - $47.74

Q3 2022

Shares 11,199 Value ($000) $495 Avg Close $42.14 Range $35.95 - $48.82

Q2 2022

Shares 11,086 Value ($000) $410 Avg Close $37.71 Range $31.46 - $44.42

Q4 2018

Shares 5,341 Value ($000) $289 Avg Close $51.00 Range $43.27 - $59.81

Q3 2018

Shares 5,341 Value ($000) $275 Avg Close $46.98 Range $41.05 - $54.85

Q2 2018

Shares 20,952 Value ($000) $873 Avg Close $44.30 Range $39.07 - $51.00

Q1 2018

Shares 6,040 Value ($000) $266 Avg Close $50.80 Range $43.38 - $56.47

Q4 2017

Shares 10,872 Value ($000) $547 Avg Close $54.84 Range $50.02 - $65.51

Q3 2017

Shares 23,772 Value ($000) $1,205 Avg Close $52.38 Range $43.75 - $60.01

Q2 2017

Shares 29,412 Value ($000) $1,496 Avg Close $46.57 Range $37.26 - $55.73

Q1 2017

Shares 30,811 Value ($000) $1,239 Avg Close $44.91 Range $37.29 - $56.91

Q4 2016

Shares 43,207 Value ($000) $2,067 Avg Close $39.57 Range $24.58 - $57.00

Q3 2016

Shares 20,441 Value ($000) $749 Avg Close $31.29 Range $23.26 - $40.82

Q2 2016

Shares 20,516 Value ($000) $478 Avg Close $32.26 Range $19.59 - $46.75

Q1 2016

Shares 16,568 Value ($000) $671 Avg Close $40.62 Range $30.93 - $62.68

Q4 2015

Shares 16,769 Value ($000) $1,039 Avg Close $53.96 Range $38.30 - $65.34

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	108,044	$8,547	$75.30	$64.93 - $83.61
Q3 2025	114,743	$7,506	$48.82	$39.72 - $65.55
Q2 2025	114,623	$4,529	$32.73	$23.95 - $40.61
Q1 2025	102,473	$3,092	$32.75	$29.61 - $35.48
Q4 2024	96,631	$3,378	$37.38	$33.33 - $40.58
Q3 2024	64,874	$2,599	$46.53	$39.48 - $52.34
Q2 2024	14,312	$682	$41.01	$35.95 - $47.86
Q1 2024	14,234	$617	$47.67	$41.60 - $54.44
Q4 2023	13,998	$708	$47.90	$41.84 - $52.27
Q3 2023	15,534	$705	$41.26	$38.26 - $47.72
Q2 2023	15,206	$624	$38.43	$34.32 - $43.55
Q1 2023	15,132	$541	$37.55	$32.69 - $41.73
Q4 2022	10,985	$415	$42.06	$36.69 - $47.74
Q3 2022	11,199	$495	$42.14	$35.95 - $48.82
Q2 2022	11,086	$410	$37.71	$31.46 - $44.42
Q4 2018	5,341	$289	$51.00	$43.27 - $59.81
Q3 2018	5,341	$275	$46.98	$41.05 - $54.85
Q2 2018	20,952	$873	$44.30	$39.07 - $51.00
Q1 2018	6,040	$266	$50.80	$43.38 - $56.47
Q4 2017	10,872	$547	$54.84	$50.02 - $65.51
Q3 2017	23,772	$1,205	$52.38	$43.75 - $60.01
Q2 2017	29,412	$1,496	$46.57	$37.26 - $55.73
Q1 2017	30,811	$1,239	$44.91	$37.29 - $56.91
Q4 2016	43,207	$2,067	$39.57	$24.58 - $57.00
Q3 2016	20,441	$749	$31.29	$23.26 - $40.82
Q2 2016	20,516	$478	$32.26	$19.59 - $46.75
Q1 2016	16,568	$671	$40.62	$30.93 - $62.68
Q4 2015	16,769	$1,039	$53.96	$38.30 - $65.34