IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

EAM Investors, LLC's Holding History (CIK: 0001510989)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 53,914 Value ($000) $4,265 Avg Close $75.30 Range $64.93 - $83.61

Q3 2025

Shares 54,977 Value ($000) $3,538 Avg Close $48.82 Range $39.72 - $65.55

Q3 2023

Shares 29,262 Value ($000) $1,327 Avg Close $41.26 Range $38.26 - $47.72

Q3 2022

Shares 28,396 Value ($000) $1,256 Avg Close $42.14 Range $35.95 - $48.82

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	53,914	$4,265	$75.30	$64.93 - $83.61
Q3 2025	54,977	$3,538	$48.82	$39.72 - $65.55
Q3 2023	29,262	$1,327	$41.26	$38.26 - $47.72
Q3 2022	28,396	$1,256	$42.14	$35.95 - $48.82