IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Parametrica Management Ltd's Holding History (CIK: 0001535110)

Note: Option positions (PUT/CALL) are excluded.

Q2 2022

Shares 6,165 Value ($000) $228 Avg Close $37.71 Range $31.46 - $44.42

Q4 2018

Shares 4,161 Value ($000) $225 Avg Close $51.00 Range $43.27 - $59.81

Q2 2017

Shares 5,849 Value ($000) $298 Avg Close $46.57 Range $37.26 - $55.73

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2022	6,165	$228	$37.71	$31.46 - $44.42
Q4 2018	4,161	$225	$51.00	$43.27 - $59.81
Q2 2017	5,849	$298	$46.57	$37.26 - $55.73