IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Allianz Asset Management GmbH's Holding History (CIK: 0001535323)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 16,716 Value ($000) $1,322 Avg Close $75.30 Range $64.93 - $83.61

Q3 2025

Shares 11,500 Value ($000) $752 Avg Close $48.82 Range $39.72 - $65.55

Q2 2023

Shares 23,100 Value ($000) $948 Avg Close $38.43 Range $34.32 - $43.55

Q1 2023

Shares 108,248 Value ($000) $3,869 Avg Close $37.55 Range $32.69 - $41.73

Q4 2022

Shares 102,487 Value ($000) $3,871 Avg Close $42.06 Range $36.69 - $47.74

Q3 2022

Shares 28,880 Value ($000) $1,278 Avg Close $42.14 Range $35.95 - $48.82

Q2 2022

Shares 22,497 Value ($000) $833 Avg Close $37.71 Range $31.46 - $44.42

Q1 2022

Shares 81,830 Value ($000) $3,031 Avg Close $32.73 Range $28.25 - $37.15

Q4 2021

Shares 81,830 Value ($000) $2,491 Avg Close $31.48 Range $25.04 - $35.80

Q3 2021

Shares 19,710 Value ($000) $661 Avg Close $37.68 Range $33.52 - $40.99

Q2 2021

Shares 19,710 Value ($000) $786 Avg Close $39.17 Range $34.43 - $47.87

Q1 2021

Shares 34,844 Value ($000) $1,566 Avg Close $55.77 Range $41.42 - $64.37

Q4 2020

Shares 34,844 Value ($000) $1,971 Avg Close $49.83 Range $45.09 - $60.95

Q2 2020

Shares 4,192 Value ($000) $247 Avg Close $55.63 Range $45.12 - $61.24

Q1 2020

Shares 4,992 Value ($000) $236 Avg Close $55.74 Range $39.32 - $64.34

Q4 2019

Shares 6,092 Value ($000) $368 Avg Close $59.58 Range $53.34 - $66.22

Q3 2019

Shares 6,407 Value ($000) $384 Avg Close $65.17 Range $58.48 - $73.09

Q2 2019

Shares 5,863 Value ($000) $377 Avg Close $70.69 Range $61.91 - $86.58

Q1 2019

Shares 10,733 Value ($000) $871 Avg Close $64.51 Range $52.45 - $81.59

Q4 2018

Shares 55,243 Value ($000) $2,944 Avg Close $51.00 Range $43.27 - $59.81

Q3 2018

Shares 59,380 Value ($000) $3,063 Avg Close $46.98 Range $41.05 - $54.85

Q2 2018

Shares 59,380 Value ($000) $2,474 Avg Close $44.30 Range $39.07 - $51.00

Q1 2018

Shares 59,380 Value ($000) $2,618 Avg Close $50.80 Range $43.38 - $56.47

Q4 2017

Shares 68,880 Value ($000) $3,465 Avg Close $54.84 Range $50.02 - $65.51

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	16,716	$1,322	$75.30	$64.93 - $83.61
Q3 2025	11,500	$752	$48.82	$39.72 - $65.55
Q2 2023	23,100	$948	$38.43	$34.32 - $43.55
Q1 2023	108,248	$3,869	$37.55	$32.69 - $41.73
Q4 2022	102,487	$3,871	$42.06	$36.69 - $47.74
Q3 2022	28,880	$1,278	$42.14	$35.95 - $48.82
Q2 2022	22,497	$833	$37.71	$31.46 - $44.42
Q1 2022	81,830	$3,031	$32.73	$28.25 - $37.15
Q4 2021	81,830	$2,491	$31.48	$25.04 - $35.80
Q3 2021	19,710	$661	$37.68	$33.52 - $40.99
Q2 2021	19,710	$786	$39.17	$34.43 - $47.87
Q1 2021	34,844	$1,566	$55.77	$41.42 - $64.37
Q4 2020	34,844	$1,971	$49.83	$45.09 - $60.95
Q2 2020	4,192	$247	$55.63	$45.12 - $61.24
Q1 2020	4,992	$236	$55.74	$39.32 - $64.34
Q4 2019	6,092	$368	$59.58	$53.34 - $66.22
Q3 2019	6,407	$384	$65.17	$58.48 - $73.09
Q2 2019	5,863	$377	$70.69	$61.91 - $86.58
Q1 2019	10,733	$871	$64.51	$52.45 - $81.59
Q4 2018	55,243	$2,944	$51.00	$43.27 - $59.81
Q3 2018	59,380	$3,063	$46.98	$41.05 - $54.85
Q2 2018	59,380	$2,474	$44.30	$39.07 - $51.00
Q1 2018	59,380	$2,618	$50.80	$43.38 - $56.47
Q4 2017	68,880	$3,465	$54.84	$50.02 - $65.51