IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

SABBY MANAGEMENT, LLC's Holding History (CIK: 0001535610)

Note: Option positions (PUT/CALL) are excluded.

Q3 2021

Shares 84,600 Value ($000) $2,837 Avg Close $37.68 Range $33.52 - $40.99

Q2 2021

Shares 78,000 Value ($000) $3,111 Avg Close $39.17 Range $34.43 - $47.87

Q1 2021

Shares 54,688 Value ($000) $2,459 Avg Close $55.77 Range $41.42 - $64.37

Q1 2017

Shares 115,694 Value ($000) $4,651 Avg Close $44.91 Range $37.29 - $56.91

Q1 2016

Shares 7,002 Value ($000) $284 Avg Close $40.62 Range $30.93 - $62.68

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2021	84,600	$2,837	$37.68	$33.52 - $40.99
Q2 2021	78,000	$3,111	$39.17	$34.43 - $47.87
Q1 2021	54,688	$2,459	$55.77	$41.42 - $64.37
Q1 2017	115,694	$4,651	$44.91	$37.29 - $56.91
Q1 2016	7,002	$284	$40.62	$30.93 - $62.68