IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Crossmark Global Holdings, Inc.'s Holding History (CIK: 0001539204)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 3,102 Value ($000) $245 Avg Close $75.30 Range $64.93 - $83.61

Q4 2017

Shares 5,096 Value ($000) $256 Avg Close $54.84 Range $50.02 - $65.51

Q3 2017

Shares 5,018 Value ($000) $254 Avg Close $52.38 Range $43.75 - $60.01

Q3 2016

Shares 5,018 Value ($000) $254 Avg Close $31.29 Range $23.26 - $40.82

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	3,102	$245	$75.30	$64.93 - $83.61
Q4 2017	5,096	$256	$54.84	$50.02 - $65.51
Q3 2017	5,018	$254	$52.38	$43.75 - $60.01
Q3 2016	5,018	$254	$31.29	$23.26 - $40.82