IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Focus Partners Wealth's Holding History (CIK: 0001542153)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 181,817 Value ($000) $14,384 Avg Close $75.30 Range $64.93 - $83.61

Q2 2025

Shares 10,056 Value ($000) $397 Avg Close $32.73 Range $23.95 - $40.61

Q1 2025

Shares 9,832 Value ($000) $297 Avg Close $32.75 Range $29.61 - $35.48

Q4 2024

Shares 7,555 Value ($000) $282 Avg Close $37.38 Range $33.33 - $40.58

Q3 2024

Shares 5,696 Value ($000) $228 Avg Close $46.53 Range $39.48 - $52.34

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	181,817	$14,384	$75.30	$64.93 - $83.61
Q2 2025	10,056	$397	$32.73	$23.95 - $40.61
Q1 2025	9,832	$297	$32.75	$29.61 - $35.48
Q4 2024	7,555	$282	$37.38	$33.33 - $40.58
Q3 2024	5,696	$228	$46.53	$39.48 - $52.34