IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Bank Julius Baer & Co. Ltd, Zurich's Holding History (CIK: 0001544599)

Note: Option positions (PUT/CALL) are excluded.

Q1 2024

Shares 14,230 Value ($000) $571 Avg Close $47.67 Range $41.60 - $54.44

Q4 2023

Shares 9,050 Value ($000) $458 Avg Close $47.90 Range $41.84 - $52.27

Q2 2021

Shares 288,844 Value ($000) $11,522 Avg Close $39.17 Range $34.43 - $47.87

Q1 2021

Shares 287,927 Value ($000) $12,945 Avg Close $55.77 Range $41.42 - $64.37

Q2 2020

Shares 195,993 Value ($000) $11,522 Avg Close $55.63 Range $45.12 - $61.24

Q1 2020

Shares 274,081 Value ($000) $12,945 Avg Close $55.74 Range $39.32 - $64.34

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2024	14,230	$571	$47.67	$41.60 - $54.44
Q4 2023	9,050	$458	$47.90	$41.84 - $52.27
Q2 2021	288,844	$11,522	$39.17	$34.43 - $47.87
Q1 2021	287,927	$12,945	$55.77	$41.42 - $64.37
Q2 2020	195,993	$11,522	$55.63	$45.12 - $61.24
Q1 2020	274,081	$12,945	$55.74	$39.32 - $64.34