IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Private Advisor Group, LLC's Holding History (CIK: 0001567755)

Note: Option positions (PUT/CALL) are excluded.

Q1 2025

Shares 34,531 Value ($000) $1,042 Avg Close $32.75 Range $29.61 - $35.48

Q4 2024

Shares 40,673 Value ($000) $1,422 Avg Close $37.38 Range $33.33 - $40.58

Q3 2024

Shares 43,787 Value ($000) $1,754 Avg Close $46.53 Range $39.48 - $52.34

Q2 2024

Shares 46,426 Value ($000) $2,213 Avg Close $41.01 Range $35.95 - $47.86

Q1 2024

Shares 47,976 Value ($000) $2,080 Avg Close $47.67 Range $41.60 - $54.44

Q4 2023

Shares 48,807 Value ($000) $2,469 Avg Close $47.90 Range $41.84 - $52.27

Q3 2023

Shares 48,618 Value ($000) $2,205 Avg Close $41.26 Range $38.26 - $47.72

Q2 2023

Shares 47,830 Value ($000) $1,962 Avg Close $38.43 Range $34.32 - $43.55

Q1 2023

Shares 48,467 Value ($000) $1,732 Avg Close $37.55 Range $32.69 - $41.73

Q4 2022

Shares 51,008 Value ($000) $2 Avg Close $42.06 Range $36.69 - $47.74

Q3 2022

Shares 109,872 Value ($000) $4,860 Avg Close $42.14 Range $35.95 - $48.82

Q2 2022

Shares 137,782 Value ($000) $5,101 Avg Close $37.71 Range $31.46 - $44.42

Q1 2022

Shares 156,968 Value ($000) $5,814 Avg Close $32.73 Range $28.25 - $37.15

Q4 2021

Shares 115,742 Value ($000) $3,522 Avg Close $31.48 Range $25.04 - $35.80

Q3 2021

Shares 44,105 Value ($000) $1,480 Avg Close $37.68 Range $33.52 - $40.99

Q2 2021

Shares 23,441 Value ($000) $935 Avg Close $39.17 Range $34.43 - $47.87

Q1 2021

Shares 18,042 Value ($000) $811 Avg Close $55.77 Range $41.42 - $64.37

Q4 2020

Shares 14,781 Value ($000) $836 Avg Close $49.83 Range $45.09 - $60.95

Q2 2020

Shares 1,309 Value ($000) $77 Avg Close $55.63 Range $45.12 - $61.24

Q1 2019

Shares 4,360 Value ($000) $354 Avg Close $64.51 Range $52.45 - $81.59

Q3 2018

Shares 4,611 Value ($000) $238 Avg Close $46.98 Range $41.05 - $54.85

Q4 2017

Shares 4,481 Value ($000) $231 Avg Close $54.84 Range $50.02 - $65.51

Q3 2017

Shares 4,970 Value ($000) $274 Avg Close $52.38 Range $43.75 - $60.01

Q2 2017

Shares 5,102 Value ($000) $263 Avg Close $46.57 Range $37.26 - $55.73

Q4 2015

Shares 3,673 Value ($000) $227 Avg Close $53.96 Range $38.30 - $65.34

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2025	34,531	$1,042	$32.75	$29.61 - $35.48
Q4 2024	40,673	$1,422	$37.38	$33.33 - $40.58
Q3 2024	43,787	$1,754	$46.53	$39.48 - $52.34
Q2 2024	46,426	$2,213	$41.01	$35.95 - $47.86
Q1 2024	47,976	$2,080	$47.67	$41.60 - $54.44
Q4 2023	48,807	$2,469	$47.90	$41.84 - $52.27
Q3 2023	48,618	$2,205	$41.26	$38.26 - $47.72
Q2 2023	47,830	$1,962	$38.43	$34.32 - $43.55
Q1 2023	48,467	$1,732	$37.55	$32.69 - $41.73
Q4 2022	51,008	$2	$42.06	$36.69 - $47.74
Q3 2022	109,872	$4,860	$42.14	$35.95 - $48.82
Q2 2022	137,782	$5,101	$37.71	$31.46 - $44.42
Q1 2022	156,968	$5,814	$32.73	$28.25 - $37.15
Q4 2021	115,742	$3,522	$31.48	$25.04 - $35.80
Q3 2021	44,105	$1,480	$37.68	$33.52 - $40.99
Q2 2021	23,441	$935	$39.17	$34.43 - $47.87
Q1 2021	18,042	$811	$55.77	$41.42 - $64.37
Q4 2020	14,781	$836	$49.83	$45.09 - $60.95
Q2 2020	1,309	$77	$55.63	$45.12 - $61.24
Q1 2019	4,360	$354	$64.51	$52.45 - $81.59
Q3 2018	4,611	$238	$46.98	$41.05 - $54.85
Q4 2017	4,481	$231	$54.84	$50.02 - $65.51
Q3 2017	4,970	$274	$52.38	$43.75 - $60.01
Q2 2017	5,102	$263	$46.57	$37.26 - $55.73
Q4 2015	3,673	$227	$53.96	$38.30 - $65.34