IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Advocacy Wealth Management Services, LLC's Holding History (CIK: 0001569452)

Note: Option positions (PUT/CALL) are excluded.

Q3 2016

Shares 700 Value ($000) $26 Avg Close $31.29 Range $23.26 - $40.82

Q2 2016

Shares 700 Value ($000) $16 Avg Close $32.26 Range $19.59 - $46.75

Q1 2016

Shares 700 Value ($000) $28 Avg Close $40.62 Range $30.93 - $62.68

Q4 2015

Shares 500 Value ($000) $31 Avg Close $53.96 Range $38.30 - $65.34

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2016	700	$26	$31.29	$23.26 - $40.82
Q2 2016	700	$16	$32.26	$19.59 - $46.75
Q1 2016	700	$28	$40.62	$30.93 - $62.68
Q4 2015	500	$31	$53.96	$38.30 - $65.34